Inner Speech is not so Simple: A Commentary on Cho and Wu (2013)

Inner Speech is not so Simple: A Commentary on Cho and Wu (2013)

We welcome Cho and Wu’s (1) suggestion that the study of auditory verbal hallucinations (AVHs) could be improved by contrasting and testing more explanatory models. However, we have some worries both about their criticisms of inner speech-based self-monitoring (ISS) models and whether their proposed spontaneous activation (SA) model is explanatory. Cho and Wu rightly point out that some phenome...

Inner speech is not so simple : a commentary on Cho & Wu ( 2013 )

Ending the Message Is Not So Simple

splicing. Instead it can effectively be considered a regulator of the poly(A) signal. The associated U1SnRNP may Sir William Dunn School of Pathology Chemical Pathology Unit in this context act as a poly(A) factor rather than splicing factor. Furthermore U1SnRNP has been shown to cross-University of Oxford South Parks Road link with poly(A) signals and may have a key function in defining the la...

Commentary on Wu and Ma.

Fisher (1947) and Bailey (1961) considered a two-locus tetrasomic model and exploited the basic features of genetic segregation and linkage of tetrasomic inheritance. They attempted to establish the relationship between the model parameters (the coefficients of double reduction at two linked loci, say α and β respectively, and recombination frequency between them, r) and frequencies of gamete m...

A not so simple analgesic

Many of the common causes of a high anion gap metabolic acidosis, like salicylate toxicity or diabetic ketoacidosis, are well recognized and promptly treated. Pyroglutamic acidosis (or 5-oxoproline acidosis) is a less common cause and is likely substantially underdiagnosed for two reasons: firstly, urine or serum measurements of pyroglutamic acid are performed only in specialist laboratories, a...